' 
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 1 Review
8.6
Supplement Facts
Serving Size: 1 Vegetarian Capsule
Amount Per Serving
%DV
Folate (as L-5-Methyltetrahydrofolate calcium salt)
680 mcg°
170%
Vitamin B12 (as methylcobalamin)
300 mcg
12,500%
Top Medical Research Studies
8
Folate may protect against OSA
The relation of dietary components with severity of obstructive sleep apnea in Cypriot patients: A randomized, stratified epidemiological study.
Folate's impact on sleep apnea
We conducted a thorough investigation into how dietary components, particularly folate, relate to the severity of obstructive sleep apnea (OSA) in a group of adults living in Cyprus. Our study included a diverse sample of 303 participants aged over 18, who completed detailed food frequency and physical activity questionnaires, along with undergoing sleep studies to assess OSA severity.
In our analysis, we found that patients with more severe OSA, identified by a higher apnea-hypopnea index (AHI), had significant characteristics such as increased body mass index (BMI) and higher caloric intake. Interestingly, those with moderate to severe OSA reported higher folic acid consumption compared to those with milder forms of the condition.
This suggests that while greater energy intake appears to correlate with more severe OSA, a higher intake of folate may offer some protective benefits. However, it’s essential to note that we did not isolate the effects of folate alone, as other dietary factors were also at play in our findings, making further research necessary to draw stronger conclusions.
Overall, our results point towards the complexity of dietary influences on sleep apnea severity, highlighting folate as a potentially beneficial nutrient alongside other lifestyle factors.
In our analysis, we found that patients with more severe OSA, identified by a higher apnea-hypopnea index (AHI), had significant characteristics such as increased body mass index (BMI) and higher caloric intake. Interestingly, those with moderate to severe OSA reported higher folic acid consumption compared to those with milder forms of the condition.
This suggests that while greater energy intake appears to correlate with more severe OSA, a higher intake of folate may offer some protective benefits. However, it’s essential to note that we did not isolate the effects of folate alone, as other dietary factors were also at play in our findings, making further research necessary to draw stronger conclusions.
Overall, our results point towards the complexity of dietary influences on sleep apnea severity, highlighting folate as a potentially beneficial nutrient alongside other lifestyle factors.
Read More
Most Useful Reviews
9.5
Twitching resolved
I had a twitch in my left eye for two months. After taking folic acid with B12 and researching methylfolate, I purchased a new supplement. Within a week, the twitching subsided. I now sleep well without disturbance, a welcome change after four years of disrupted sleep. I'm currently taking it alongside B6 from Solgar for better absorption.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
- All Researches
8
Folate may protect against OSA
The relation of dietary components with severity of obstructive sleep apnea in Cypriot patients: A randomized, stratified epidemiological study.
Folate's impact on sleep apnea
We conducted a thorough investigation into how dietary components, particularly folate, relate to the severity of obstructive sleep apnea (OSA) in a group of adults living in Cyprus. Our study included a diverse sample of 303 participants aged over 18, who completed detailed food frequency and physical activity questionnaires, along with undergoing sleep studies to assess OSA severity.
In our analysis, we found that patients with more severe OSA, identified by a higher apnea-hypopnea index (AHI), had significant characteristics such as increased body mass index (BMI) and higher caloric intake. Interestingly, those with moderate to severe OSA reported higher folic acid consumption compared to those with milder forms of the condition.
This suggests that while greater energy intake appears to correlate with more severe OSA, a higher intake of folate may offer some protective benefits. However, it’s essential to note that we did not isolate the effects of folate alone, as other dietary factors were also at play in our findings, making further research necessary to draw stronger conclusions.
Overall, our results point towards the complexity of dietary influences on sleep apnea severity, highlighting folate as a potentially beneficial nutrient alongside other lifestyle factors.
In our analysis, we found that patients with more severe OSA, identified by a higher apnea-hypopnea index (AHI), had significant characteristics such as increased body mass index (BMI) and higher caloric intake. Interestingly, those with moderate to severe OSA reported higher folic acid consumption compared to those with milder forms of the condition.
This suggests that while greater energy intake appears to correlate with more severe OSA, a higher intake of folate may offer some protective benefits. However, it’s essential to note that we did not isolate the effects of folate alone, as other dietary factors were also at play in our findings, making further research necessary to draw stronger conclusions.
Overall, our results point towards the complexity of dietary influences on sleep apnea severity, highlighting folate as a potentially beneficial nutrient alongside other lifestyle factors.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Review
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Twitching resolved
I had a twitch in my left eye for two months. After taking folic acid with B12 and researching methylfolate, I purchased a new supplement. Within a week, the twitching subsided. I now sleep well without disturbance, a welcome change after four years of disrupted sleep. I'm currently taking it alongside B6 from Solgar for better absorption.
Read More
